SEVA-101 is an off-the-shelf, intra-articular regenerative therapy developed to treat osteoarthritis in companion animals. Built on the same platform used for human health, SEVA-101 has shown robust cartilage regeneration in preclinical models delivering disease-modifying results that go beyond managing pain.

A Regenerative Solution for Companion Animals

  • True disease modification: Acts at the source of osteoarthritic degeneration, not just its symptoms.

  • Improved mobility and quality of life: Regenerates cartilage and slows disease progression.

  • Minimally invasive: Delivered as a convenient intra-articular injection.

Built for Scalability, Backed by Science

Using iPSC-derived cartilage, SEVA-101 offers consistent, high-quality exosomes rich in regenerative factors including proteins, lipids, and nucleic acids and optimized for veterinary application.

Multi-Pathway Impact

SEVA-101 targets pathways critical to:

  • Joint tissue repair

  • Inflammation resolution

  • Cartilage health and regeneration

This multi-modal, disease-modifying mechanism supports long-term joint health and function, offering a powerful new approach for managing OA in pets.

SEVA-101 contents are known to promote key pathways in Cartilage Regeneration, Extracellular Matrix Production, Reduced Inflammation, and Chondrogenic Differentiation suggesting a multi-modal MOA.